You will also receive a separate invoice from the laboratory performing the test by mail (the costs are currently approximately EUR 29.14 for self-payers).

Vitamin K2 MK7 is important:

- for bone metabolism, because K2, in cooperation with vitamin D, ensures that calcium is not deposited in the vessels but is incorporated into the bones (and teeth)
- Vitamins D and K work together in a calcium-dependent regulatory network that counteracts the development of chronic inflammatory diseases.
- for indirect protection against arteriosclerosis and heart attacks
- to improve bone density (protection against osteopenia, osteoporosis, hip fractures, femoral neck fractures, etc.)
- for healthy kidney function
- is needed in the liver to produce certain clotting factors that are important for blood clotting
and much more


Problem of vitamin K2 analysis in blood

Although vitamin K2 can be measured in the blood, the values obtained do not adequately reflect the body's vitamin K2 supply. The reasons for this are:

- The blood level records the daily intake, but not the supply to the body tissue.
- Usually only MK4 and MK7 are measured.
- The examination is complicated; the serum must be sent to the laboratory frozen.
- The half-life of vitamin K is very short (a few hours).


The solution:
uc Osteocalcin as a stable biomarker of vitamin K2 status

Vitamin K2 is a vital cofactor for the carboxylation of osteocalcin, i.e., the conversion of undercarboxylated "uc" osteocalcin into its carboxylated form. In cases of poor vitamin K2 supply or lower bioactivity, only a small proportion of osteocalcin is carboxylated. This leads to an increase in ucOsteocalcin. ucOsteocalcin in serum can now be determined with this simple test. Elevated levels indicate an absolute and/or functional vitamin K2 deficiency:

Increased ucOsteocalcin increases the risk of various chronic inflammatory diseases, such as type 2 diabetes and atherosclerosis.

In addition, postmenopausal women show a clear association with lower bone density and an increased risk of fractures.

This is attributed to a reduced formation of the carboxylated, calcium-binding osteocalcin, which inhibits bone formation.